Gas anti-solvent fractionation of natural products

Gas anti-solvent fractionation of natural products

Process Technology Proceedings

Publisher Summary Gas anti-solvent fractionation (GAS) is a relatively new separation technique that utilizes the anti-solvent power of a near-critical gas when dissolved in organic solvents. The solubility of the gas, in the solvent, increases with pressure and the solvent power decreases. Closely associated with the decrease in solvent power is the expansion of the liquid phase volume. CO2 is the most suitable gas anti-solvent because of its convenient critical temperature and high solubility in most commonly used organic solvents, such as hexane, acetone, and ethanol. This chapter describes an experiment to examine the effects of temperature, pressure, and composition of the solvent phase on the separation of lecithin from soya oil and coriander triglycerides from essential oil at a lab scale. The degree of separation was correlated against the volume expansion of the liquid phase. The precipitation of lecithin as a function of volume expansion was similar for the pure component and in mixtures with soya oil. The pressure required to achieve separation from the mixture increased relative to the pure component for lecithin but was unchanged for soya oil. High expansion levels were required to achieve the separation of triglycerides from essential oil.

1996-01-01

Catchpole, O.J.

Hochmann, S.

Anderson, S.R.J.

von Rohr, Ph. Rudolf

Trepp, Ch.

Book Section

Y8P9CKAZ

0921-8610